ABSTRACT
Parkinson′s disease (PD) is the second most common neurodegenerative disease following Alzheimer′s disease, including motor and non-motor symptoms. Non-motor symptoms are mainly autonomic nervous dysfunction, which occur about 5-20 years earlier than motor symptoms. Abnormal blood pressure regulation is a common manifestation of autonomic nervous dysfunction. Long-term abnormal blood pressure can seriously hamper the quality of life and trigger deterioration of motor symptoms. Thus, it is necessary to obtain correct understanding of the etiology, mechanism, clinical features, diagnosis and treatment of PD with blood pressure regulation disorders in order to reduce the mortality rate and the burden of medical health. This article reviews the influencing factors, characteristics, mechanisms and management of PD with blood pressure regulation disorder.
ABSTRACT
Parkinson′s disease (PD) is the second most common neurodegenerative disease following Alzheimer′s disease, including motor and non?motor symptoms. Non?motor symptoms are mainly autonomic nervous dysfunction,which occur about 5-20 years earlier than motor symptoms. Abnormal blood pressure regulation is a common manifestation of autonomic nervous dysfunction. Long?term abnormal blood pressure can seriously hamper the quality of life and trigger deterioration of motor symptoms. Thus, it is necessary to obtain correct understanding of the etiology, mechanism, clinical features, diagnosis and treatment of PD with blood pressure regulation disorders in order to reduce the mortality rate and the burden of medical health. This article reviews the influencing factors,characteristics,mechanisms and management of PD with blood pressure regulation disorder.